Secondary Hypertension due to a Renin-secreting Juxtaglomerular Cell Tumor

Paraneoplastic secondary hypertension due to a renin-secreting desmoplastic small round cell tumor: A case report

Desmoplastic small round cell tumor (DSRCT) is a rare and aggressive malignancy with a poor outcome that occurs in adolescents and young adults; <200 cases of DSRCT have been reported. Renin-producing tumors are also rare and cases of extrarenal renin-producing tumors are even rarer. The present study describes the case of a 20-year-old male that was diagnosed with DSRCT and presented with seve...

Renin‑secreting juxtaglomerular cell tumor of the kidney causing severe hypertension and polyuria.

A 22-year-old woman with hypertension and hypokalemia due to a juxtaglomerular cell tumor.

Secondary hypertension is responsible for less than 10% of cases of hypertension. If associated with hypokalemia, it may be due to primary or secondary hyperaldostronism, the latter being rarely caused by renin-secreting tumors. We present a 22-year-old woman with a history of hypertension and repeated hypokalemia, who was finally diagnosed with a small renin-secreting tumor after extensive par...

Secondary hypertension due to a renin-producing teratoma.

Twenty cases of extrarenal renin-secreting tumors have been reported, but this is the first case of a renin-producing teratoma. The patient was a 17-year-old African American girl who presented with hypertension and hypokalemia, and who was documented to have a plasma aldosterone-to-renin activity ratio consistent with secondary aldosteronism. Computed tomography demonstrated a pelvic tumor sus...

Nephron-sparing surgery for treatment of reninoma: a rare renin secreting tumor causing secondary hypertension

MAIN FINDINGS A 25-year-old hypertensive female patient was referred to our institution. Initial workup exams demonstrated a 2.8 cm cortical lower pole tumor in the right kidney. She underwent laparoscopic partial nephrectomy without complications. Histopathologic examination revealed a rare juxtaglomerular cell tumor known as reninoma. After surgery, she recovered uneventfully and all medicati...